Manx Syndrome is a colloquial
name given to the condition which
results when the mutant tailless gene
responsible for shortening the cats'
spine has an excessive negative effect.
It can seriously damage the spinal cord
and the nerves. The cat can have
problems with spina bifida, bowels,
bladder, and digestion as a
result.
Actual occurrences of this are rare in
modern examples of the breed due to
informed breeding practices. Most
pedigreed cats are not placed until
four months of age to make sure that
proper socialisation has occurred. This
gives adequate time for any mutant
gene-related health issues to be seen,
as they turn up early in the cat's
life.
According to Robinson's Genetics for
Cat Breeders and Veterinarians, both
the Manx tailless gene and the Scottish
Fold fold-eared gene are potential
lethal genes in utero if extreme
tailless to tailless are mated or if
extreme fold-eared to fold-eared are
mated. Problems are most likely to
occur when two completely tailless Manx
are bred together. For this reason,
responsible breeders generally breed a
'stumpy' or fully-tailed Manx with a
'rumpy' or 'rumpy riser' to minimise
the chances of serious defects. This
breeding practice is responsible for
the decreasing occurrence of spinal
problems in recent years.


